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N-[(2'-cyano[1,1'biphenyl]-4-yl)methyl]-methyl ester L-valine monohydrochloride CAS: 482577-59-3
| Nomoro ea lethathamo | XD93425 |
| Lebitso la Sehlahiswa | N-[(2'-cyano[1,1'biphenyl]-4-yl)methyl]-methyl ester L-valine monohydrochloride |
| CAS | 482577-59-3 |
| Foromo ea molek'hulela | Setšoantšo sa C20H23ClN2O2 |
| Boima ba Molek'hule | 358.86 |
| Lintlha tsa polokelo | Ambient |
Tlhaloso ea Sehlahisoa
| Ponahalo | Phofo e tšoeu |
| Assay | 99% mets |
N-[(2'-cyano[1,1'biphenyl] -4-yl) methyl]-methyl ester L-valine monohydrochloride ke meriana e atisang ho sebelisoa ho phekola khatello ea mali, e tsejoang hape e le khatello e phahameng ea mali.Ke ea sehlopha sa lithethefatsi tse bitsoang angiotensin-converting enzyme (ACE) inhibitors. Khatello e phahameng ea mali ke boemo bo tloaelehileng bo ka eketsang kotsi ea mathata a mangata a bophelo bo botle, ho akarelletsa le lefu la pelo, stroke, le tšenyo ea liphio.Li-inhibitors tsa ACE, joalo ka N-[(2'-cyano[1,1'biphenyl]-4-yl)methyl]-methyl ester L-valine monohydrochloride, hangata li laeloa ho thusa ho theola khatello ea mali le ho fokotsa khatello ea pelo le pelo. methapo ea mali.Mokhoa o ka sehloohong oa ts'ebetso bakeng sa N-[(2'-cyano [1,1'biphenyl] -4-yl) methyl] -methyl ester L-valine monohydrochloride e thibela mosebetsi oa enzyme e fetolang angiotensin (ACE). ).ACE e na le boikarabelo ba ho fetola angiotensin I ho angiotensin II, vasoconstrictor e matla, e fokotsang methapo ea mali le ho phahamisa khatello ea mali.Ka ho thibela ACE, meriana ena e thusa ho thibela ho thehoa ha angiotensin II, e lebisang ho vasodilation (ho atoloha ha methapo ea mali) le ho fokotseha ha khatello ea mali.N-[(2'-cyano[1,1'biphenyl] -4-yl) )methyl]-methyl ester L-valine monohydrochloride hangata e nooa ka molomo, hangata e le tekanyetso ea hang ka letsatsi.Tekanyetso e khethehileng le khafetsa ea tsamaiso li tla itšetleha ka lintlha tse fapaneng, ho kenyelletsa le ho teba ha khatello ea mali le karabelo ea motho kalafong.Meriana ena e ka sebelisoa e le mong kapa hammoho le lithethefatsi tse ling tsa antihypertensive ho finyella taolo e nepahetseng ea khatello ea mali. Ester L-valine monohydrochloride e ka baka litla-morao tse itseng ho batho ba bang.Litla-morao tse tloaelehileng li kenyelletsa ho tsekela, hlooho, sefuba se omeletseng, le mokhathala.Haeba litla-morao tsena li tsoela pele kapa li khathatsa, ho khothaletsoa ho buisana le setsebi sa bophelo bo botle.Maemong a sa tloaelehang, ho ka ba le litla-morao tse tebileng, tse kang ho kula, mathata a liphio, kapa angioedema (ho ruruha ho matla ha sefahleho, molomo, 'metso kapa leleme).Haeba ho na le litla-morao tse matla, ho lokela ho batloa tlhokomelo ea meriana hang-hang.Pele ho qala N-[(2'-cyano[1,1'biphenyl] -4-yl)methyl]-methyl ester L-valine monohydrochloride, ke habohlokoa. ho senola maemo afe kapa afe a teng a bongaka kapa allergy ho ngaka e fanang ka taelo.Meriana e ka 'na ea se ke ea tšoanela batho ba nang le histori ea lefu la liphio, lefu la sebete, kapa lefu la pelo, kaha le ka mpefatsa maemo ana.Ka kakaretso, N-[(2'-cyano[1,1'biphenyl]-4) -yl) methyl] -methyl ester L-valine monohydrochloride ke ACE inhibitor e sebelisetsoang ho phekola khatello ea mali.Ka ho thibela ACE, e thusa ho atolosa methapo ea mali le ho theola khatello ea mali.Ho khomarela litekanyetso tse behiloeng, ho lateloa khafetsa le litsebi tsa tlhokomelo ea bophelo, le ho beha leihlo litla-morao tse ka bang teng ke tsa bohlokoa bakeng sa tšebeliso e sireletsehileng le e sebetsang ea meriana ena.Ho bohlokoa hape ho boloka bophelo bo botle, ho kenyelletsa boikoetliso ba kamehla, lijo tse leka-lekaneng, le taolo ea khatello ea maikutlo, ho ts'ehetsa taolo ea khatello ea mali.
