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Lihlahisoa

Liraglutide Cas: 204656-20-2

Tlhaloso e Khutšoanyane:

Nomoro ea lethathamo: XD92579
Cas: 204656-20-2
Foromo ea molek'hule: C172H265N43O51
Boima ba Molek'hule: 3751.20
Boteng: E teng thepeng e teng ka lebenkeleng
Theko:  
Sephutheloana:  
Sephutheloana sa Bongata: Kopa Quote

 


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Nomoro ea lethathamo XD92579
Lebitso la Sehlahiswa Liraglutide
CAS 204656-20-2
Foromo ea molek'hulela C172H265N43O51
Boima ba Molek'hule 3751.20
Lintlha tsa polokelo Ambient

Tlhaloso ea Sehlahisoa

Ponahalo Phofo e tšoeu
Assay 99% mets

 

Mekhoa ea ho phekola T2DM, lefu le khetholloang ke ho se sebetse hantle ha lisele tsa islet le ho hanyetsa insulin, li kenyelletsa mahlahana a eketsang secretion ea insulin ka manyeme (secretagogues), mahlahana a eketsang kutlo ea litho tse lebisitsoeng ho insulin (li-sensitizers), le Liraglutide, e leng GLP-1 receptor agonist ho fihla 'marakeng, e na le 97% ea homology ho GLP-1 ka liphetoho tse peli feela tsa amino acid le tlatsetso ea ketane ea mahlakoreng a mafura a mafura.Ka ho khetheha, lysine e boemong ba 34 e nkeloe sebaka ke arginine, 'me lysine e boemong ba 26 e fetotsoe ka ketane ea C16 acyl ka glutamoyl spacer.Liraglutide e fumana khanyetso ea eona ho nyenyefatso ea DPP-4 ho tloha ho tšekamelo ea eona ea ho theha micelles le ho tlama ho albin.Ho fapana le exenatide ea pele ho eona, e hlokang liente tse peli tsa letsatsi le letsatsi pele ho lijo tsa pele le tsa ho qetela tsa letsatsi, liraglutide e amoheloa e le mokhoa oa kalafo oa hang ka letsatsi mme e ka sebelisoa hammoho le metformin kapa sulfonylurea ho bakuli ba nang le taolo e sa lekaneng ea glycemic le e 'ngoe ea tsona. monotherapy kapa kalafo e kopaneng e kopaneng.E boetse e amohetsoe hammoho le kalafo e habeli ea metformin le thiazolidinedione ho bakuli ba nang le taolo e sa lekaneng ea glycemic.Liraglutide e bonts'itse matla a tlamang a 61 pM (EC50 = 55 pM bakeng sa GLP-1) bakeng sa moamoheli oa motho oa GLP-1.


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    Liraglutide Cas: 204656-20-2