L-Octahydroindole-2-carboxylic acid CAS: 80875-98-5
Nomoro ea lethathamo | XD93404 |
Lebitso la Sehlahiswa | L-Octahydroindole-2-carboxylic acid |
CAS | 80875-98-5 |
Foromo ea molek'hulela | C9H15NO2 |
Boima ba Molek'hule | 169.22 |
Lintlha tsa polokelo | Ambient |
Tlhaloso ea Sehlahisoa
Ponahalo | Phofo e tšoeu |
Assay | 99% mets |
L-Octahydroindole-2-carboxylic acid, eo hape e tsejoang e le Octahydroindole-2-carboxylic acid, ke motsoako oa heterocyclic o nang le bohlokoa ho k'hemistri ea meriana le ea meriana.Sebopeho le thepa ea eona e ikhethang e etsa hore e be mohaho oa bohlokoa ka ho fetisisa ha ho etsoa limolek'hule tse sa tšoaneng tsa bioactive.Kopo e le 'ngoe ea bohlokoa ea L-Octahydroindole-2-carboxylic acid e ka har'a motsoako oa meriana ea meriana.Sistimi ea eona ea selikalikoe sa indole, e kopantsoeng le sehlopha sa carboxylic acid, e lumella liphetoho tse ngata tsa lik'hemik'hale.Motsoako ona o sebetsa e le setsi sa bohlokoa sa ho thehoa ha lithethefatsi tse lebisang litseleng tse itseng tsa likokoana-hloko kapa li-receptors.The indole ring system in L-Octahydroindole-2-carboxylic acid ke mokhoa o tloaelehileng o fumanoang lihlahisoa tse ngata tsa tlhaho le meriana ea meriana.Sena se kenyelletsa li-neurotransmitters tse kang serotonin, lithethefatsi tsa meriana tse kang li-antipsychotics, le li-alkaloids tse kang tryptamine.Ka ho sebelisa L-Octahydroindole-2-carboxylic acid e le ntho ea ho qala, litsebi tsa meriana li ka khona ho fihlella lilaebraring tse fapaneng tsa metsoako bakeng sa ho sibolloa ha lithethefatsi le nts'etsopele. Ho feta moo, L-Octahydroindole-2-carboxylic acid e ka fetoloa ho hlahisa lihlopha tse ling tse sebetsang kapa tse ling , ho ntlafatsa thepa ea eona ea meriana kapa khetho e lebisang lipakaneng tse itseng.Liphetoho tsena li ka finyelloa ka liphetoho tse fapaneng tsa lik'hemik'hale, tse kang acylation, alkylation, kapa amine condensation reactions.Ka ho fetola sebopeho le thepa ea L-Octahydroindole-2-carboxylic acid derivatives, bafuputsi ba ka ntlafatsa litšobotsi tsa bona tse kang tsa lithethefatsi, ho akarelletsa le bioavailability, potency, le solubility. Ntle le karolo ea eona ho nts'etsopele ea lithethefatsi, L-Octahydroindole-2-carboxylic acid e boetse e fumana lits'ebetso ho kopantseng lihlahisoa tse rarahaneng tsa tlhaho le li-analogues.Lihlahisoa tsa tlhaho tse nkiloeng ho limela, li-fungus le libaktheria hangata li na le mesebetsi e matla ea likokoana-hloko 'me li hokahanya mesebetsi ea bohlokoa ea 'mele.Sebopeho se feto-fetohang sa L-Octahydroindole-2-carboxylic acid se lumella ho hahoa ha meralo e fapaneng ea limolek'hule e etsisang kapa e fetolang meaho ea lihlahisoa tsa tlhaho, e e etsa sesebelisoa sa bohlokoa tlhahisong ea lihlahisoa tsa tlhaho le biology ea lik'hemik'hale. Ka kakaretso, L-Octahydroindole-2- carboxylic acid ke motsoako o sebetsang ka mokhoa o fapaneng o nang le ts'ebeliso ea bohlokoa ho sibolloeng ha lithethefatsi tsa meriana, motsoako oa lihlahisoa tsa tlhaho, le biology ea lik'hemik'hale.Likarolo tsa eona tse ikhethang tsa sebopeho le bokhoni ba ho etsa liphetoho tse fapaneng tsa lik'hemik'hale li e etsa moaho oa bohlokoa bakeng sa ho theha limolek'hule tsa bioactive.Ka ho kopanya le ho fetola lintho tse nkiloeng ho L-Octahydroindole-2-carboxylic acid, bafuputsi ba ka hlahloba batho ba bacha ba sebelisang lithethefatsi, ba senola litsela tsa tlhaho tsa lihlahisoa tsa tlhaho, le ho ntlafatsa kutloisiso ea rona ea mekhoa ea likokoana-hloko.