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Lihlahisoa

Ivermectin Cas: 70288-86-7

Tlhaloso e Khutšoanyane:

Nomoro ea lethathamo: XD91886
Cas: 70288-86-7
Foromo ea molek'hule: C48H74O14
Boima ba Molek'hule: 875.09
Boteng: E teng thepeng e teng ka lebenkeleng
Theko:  
Sephutheloana:  
Sephutheloana sa Bongata: Kopa Quote

 


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Nomoro ea lethathamo XD91886
Lebitso la Sehlahiswa Ivermectin
CAS 70288-86-7
Foromo ea molek'hulela C48H74O14
Boima ba Molek'hule 875.09
Lintlha tsa polokelo 2-8°C
Khoutu ea Lekhetho e Kopantsoeng 29322090

 

Tlhaloso ea Sehlahisoa

Ponahalo Phofo e tšoeu
Assay 99% mets
alpha D +71.5 ± 3° (c = 0.755 ka chloroform)
RTECS IH7891500
ho qhibiliha H2O: ≤1.0% KF
Ho qhibiliha ha Metsi 4mg/L(mocheso ha o boleloe)

 

Ivermectin (Cardomec, Eqvalan, Ivomec) ke motsoako oa 22,23-dihydro derivatives ea avermectins B1a le B1b e lokisitsoeng ke catalytic hydrogenation.Avermectins ke litho tsa lelapa la lithibela-mafu tse rarahaneng tse hlahisoang ke ho belisoa ka mofuta oa Streptomycesavermitilis.Ho sibolloa ha bona ho bile teng ka lebaka la tlhahlobo e matla ea litso bakeng sa li-anthelmintic tse tsoang mehloling ea tlhaho.Ivermectin e sebetsa ka tekanyo e tlase khahlanong le mefuta e mengata ea li-nematodes le arthropods hore parasitizeanimals.
Ivermectin e fihletse tšebeliso e atileng ea bongaka ba liphoofolo United States le linaha tse ngata lefats'eng lohle bakeng sa taolo ea li-endoparasites le ectoparasitesin liphoofolo tse ruuoang lapeng.E fumanoe e sebetsa hantle bakeng sa phekolo ea onchocerciasis ("bofofu ba nōka") ho batho, lefu la bohlokoa le bakoang ke roundwormOncocerca volvulus, e atileng Afrika Bophirimela le Bohareng, Bochabela bo Hare, le Amerika Boroa le Bohareng. Ivermectin e senya microfilariae, e sa hōlang. Mefuta ea nematode, e hlahisang letlalo le maqhutsu a linama e leng tšobotsi ea tšoaetso, 'me e ka lebisa bofofu.Liphuputso tse mabapi le mokhoa oa ts'ebetso ea ivermectin li bonts'a hore e thibela phetiso ea interneuron-motor neuron ho nematodes ka ho hlohlelletsa ho lokolloa ha GABA e thibelang li-neurotransmitter. Sethethefatsi sena se entsoe hore se fumanehe ke moetsi ka lebaka la thuso ho mananeo a kalafo a tšoanelehang ka Mokhatlo oa Lefatše oa Bophelo.

Ivermectin e na le ts'ebetso e pharaletseng ka hore e ka ama li-nematodes, likokoanyana le likokoana-hloko tsa acarine.Ke setlhare sa khetho ea onchocerciasis mme se thusa haholo kalafong ea mefuta e meng ea filariasis, strongyloidiasis, ascariasis, loiasis, le cutaneous larva migrans.E boetse e sebetsa haholo khahlanong le likokoanyana tse fapaneng.Ke setlhare sa khetho ea ho alafa batho ba tšoaelitsoeng ke Onchocerca volvulus, e sebetsang e le moriana oa microfilaricidal khahlano le li-larvae tse lulang letlalong (microfilaria).Kalafo ea selemo le selemo e ka thibela bofofu ho tsoa ho onchocerciasis ea mahlo.Ivermectin e sebetsa ka ho hlaka ho feta diethylcarbamazine ho bancroftian filariasis, 'me e fokotsa microfilaremia ho ea haufi le litekanyetso tsa zero.Ka brugian filariasis, tumello e bakoang ke diethylcarbamazine e ka ba e phahameng.E boetse e sebelisoa ho alafa larva migrans le ho hasana strongyloidiasis.Tšebeliso ea eona e sireletsehileng nakong ea bokhachane ha e e-s'o thehoe ka botlalo.


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    Ivermectin Cas: 70288-86-7