D-Glutamic acid CAS: 6893-26-1 99% Phofo e tšoeu
Nomoro ea lethathamo | XD90313 |
Lebitso la Sehlahiswa | D-Glutamic acid |
CAS | 6893-26-1 |
Foromo ea limolek'hule | C5H9NO4 |
Boima ba Molek'hule | 147.13 |
Lintlha tsa polokelo | Ambient |
Khoutu ea Lekhetho e Kopantsoeng | 29224200 |
Tlhaloso ea Sehlahisoa
Ponahalo | Phofo e tšoeu ea kristale |
Tlhahlobo | 99% |
Ho potoloha ho itseng | -31 ho ea ho -32.2 |
Litšepe tse boima | <10ppm |
AS | <1ppm |
pH | 3 - 3.5 |
SO4 | <0.020% |
Fe | <10ppm |
Tahlehelo ka ho Omisa | <0.20% |
Masalla a ho Ignition | <0.10% |
NH4 | <0.02% |
Cl | <0.02% |
Boemo ba Tharollo | >98% |
γ-Glutamyltranspeptidases (γ-GTs) e arola tlamo ea γ-glutamyl amide ea glutathione 'me e fetisetsa sehlopha sa γ-glutamyl se lokolotsoeng metsing (hydrolysis) kapa li-amino acid tse amohelang (transpeptidation).Li-enzyme tsena tse fumanehang hohle li bapala karolo ea bohlokoa ho biosynthesis le ho senyeha ha glutathione, le ho xenobiotic detoxification.Mona re tlaleha sebopeho sa kristale sa 3Å sa Bacillus licheniformis γ-GT (BlGT) le se rarahaneng sa eona se nang le l-Glu.Mehaho ea X-ray e tiisa hore BlGT ke ea N-terminal nucleophilic hydrolase superfamily mme e senola hore protheine e na le sebaka se bulehileng se bulehileng se ts'oanang le se tlalehiloeng bakeng sa enzyme ea homologous e tsoang ho Bacillus subtilis, empa e fapane le e bonoang bakeng sa γ-GT ea motho. bakeng sa γ-GTs ho tsoa ho likokoana-hloko tse ling.Lintlha li fana ka maikutlo a hore ho tlama ha l-Glu ho etsa hore ho hlophisoe mohatla oa C-terminal oa subunit e kholo ea BlGT le ho lumella ho tsebahatsoa ha sehlopha sa masala a acid a ka amehang molemong oa ho lemoha ion ea tšepe.Karolo ea mesaletsa ena mabapi le botsitso ba BlGT e ithutoa ka ho tšoaea tšebetso ea autoprocessing, enzymatic, chemical and thermal denaturation ea liphetoho tse ncha tse ncha tsa Ala.Liphetho li bonts'a hore ho nkeloa sebaka ha Asp568 ka Ala ho ama ts'ebetso ea autoprocessing le botsitso ba sebopeho sa protheine.