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Lihlahisoa

5-(Bromomethyl) -4-(4-fluorophenyl) -6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine CAS: 799842-07-2

Tlhaloso e Khutšoanyane:

Nomoro ea lethathamo: XD93416
Cas: 799842-07-2
Foromo ea molek'hule: C16H19BrFN3O2S
Boima ba Molek'hule: 416.31
Boteng: E teng thepeng e teng ka lebenkeleng
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Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Nomoro ea lethathamo XD93416
Lebitso la Sehlahiswa 5-(Bromomethyl) -4-(4-fluorophenyl) -6-isopropyl-2--[methyl(methylsulfonyl)amino]pyrimidine
CAS 799842-07-2
Foromo ea molek'hulela C16H19BrFN3O2S
Boima ba Molek'hule 416.31
Lintlha tsa polokelo Ambient

 

Tlhaloso ea Sehlahisoa

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Assay 99% mets

 

5-(Bromomethyl) -4-(4-fluorophenyl) -6-isopropyl-2--[methyl(methylsulfonyl) amino]pyrimidine ke motsoako oa lik'hemik'hale o fumanang thuso liphuputsong tse sa tšoaneng tsa lipatlisiso, tsa meriana le tsa indasteri.Motsoako ona o tsejoa ka tlhaho ea oona e fapaneng le bokhoni boo e nang le bona bakeng sa ho hlahisa limolek'hule le lithethefatsi tse ikhethang ka lebaka la sebopeho sa eona se khethehileng le lihlopha tse sebetsang hantle. lithethefatsi.Ho ba teng ha athomo ea bromine, athomo ea fluorine, sehlopha sa isopropyl, le sebopeho sa lesale la pyrimidine se etsa hore e be mohaho o motle oa ho haha ​​​​limolek'hule tse ncha tse nang le thepa e lakatsehang.Litsebi tsa lik'hemik'hale le bafuputsi ba meriana ba ka fetola le ho sebetsa motsoako ona ho hlahisa ts'ebetso e itseng kapa likarolo tsa moralo tse molemo bakeng sa ketso e lebisitsoeng ea lithethefatsi kapa thepa e ntlafetseng ea pharmacokinetic.Ho feta moo, boteng ba lihlopha tsa methyl le methylsulfonyl ka har'a motsoako li etsa hore e be molemo ho motsoako oa tlhaho.Sehlopha sa methylsulfonyl se ka ba le maikutlo a sa tšoaneng, a kang nucleophilic displacement, ho felisa, kapa oxidation, e leng se lumellang ho kenngoa ha lihlopha tse fapaneng tse sebetsang ka har'a molek'hule e lebisitsoeng.Ho feto-fetoha hona ho etsa hore e be ea bohlokoa bakeng sa ho theha metsoako e rarahaneng ea lintho tse phelang sebakeng sa laboratori.Ho feta moo, sebopeho sa motsoako se etsa hore e be molemo haholo lithutong tsa lipatlisiso.Athomo ea fluorine le likaroloana tse ling li ka kenya letsoho molemong oa 'mele kapa oa lik'hemik'hale tse ikhethang, tsa etsa hore ho be bonolo ho etsa lipatlisiso ka liketsahalo tse itseng kapa e le motsoako oa litšupiso bakeng sa lithuto tsa papiso.Hangata bafuputsi ba sebelisa metsoako e joalo ho utloisisa litšebelisano tsa likokoana-hloko, li-kinetics tsa ho ithuta, ho hlahisa mekhoa e mecha ea maiketsetso, kapa ho ntlafatsa ts'ebetso ea mekhoa e teng ea indasteri. 4-fluorophenyl) -6-isopropyl-2--[methyl(methylsulfonyl) amino]pyrimidine e ka fapana ho itšetlehile ka sebaka se itseng sa lipatlisiso kapa indasteri.Tšebeliso e ka bang teng ea komporo e fetela ka nģ'ane ho tse boletsoeng pejana, 'me molemo oa eona o ka hlahlojoa ke litsebi tsa k'hemistri, litsebi tsa meriana, biochemist, le bo-rasaense ba bang ba amehang ho sibolloeng ha lithethefatsi, saense ea lintho tse bonahalang, kapa lipatlisiso tsa limolek'hule.Ka kakaretso, 5-(Bromomethyl) -4 -(4-fluorophenyl) -6-isopropyl-2-[methyl(methylsulfonyl) amino]pyrimidine ke motsoako o nang le mekhoa e mengata e nang le tšepiso ea lipatlisiso tsa meriana, lik'hemik'hale le tsa indasteri.Sebopeho sa eona se ikhethileng le lihlopha tse sebetsang hantle li etsa hore e be sebaka se khahlehang bakeng sa ho kopanya limolek'hule tse ncha tsa lithethefatsi le ho batlisisa liphetoho tse fapaneng tsa lik'hemik'hale.Tšebeliso e ka bang teng ea komporo e pharaletse, 'me tlhahlobo e tsoelang pele ea thepa ea eona e ka bula tsela bakeng sa tsoelo-pele mafapheng a mangata a saense.


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    5-(Bromomethyl) -4-(4-fluorophenyl) -6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidine CAS: 799842-07-2