Lihlahisoa

(4R-Cis) -1,1-Dimethylethyl-6-cyanomethyl-2,2-dimethyl-1,3-dioxane-4-acetate, eo hape e tsejoang e le Ats-8, ke motsoako o khethehileng ka har'a sehlopha sa dioxane derivatives.Le hoja boitsebiso bo fokolang bo ka 'na ba e-ba teng mabapi le ts'ebeliso e nepahetseng ea Ats-8, re ka buisana ka tšebeliso e ka bang teng le thepa ea lihlahisoa tsa dioxane ka kakaretso.Li-derivatives tsa dioxane li khahlile thahasello ea lik'hemik'hale tsa meriana ka lebaka la thepa ea tsona e fapaneng le mekhoa ea phekolo e ka bang teng.Lintho tsena tse nkiloeng li bonts'itse mesebetsi ea baeloji e tšepisang mafapha a fapaneng, ho kenyeletsoa meriana, lik'hemik'hale tsa temo, le saense ea lintho tse bonahalang.Liphuputsong tsa meriana, li-derivatives tsa dioxane li 'nile tsa batlisisoa bakeng sa thepa ea tsona ea antimicrobial.Li bonts'itse litlamorao tse thibelang libaktheria le li-fungus, e leng se etsang hore e be batho ba ka bang teng bakeng sa nts'etsopele ea li-antimicrobial agents.Ho sebelisa matla a antimicrobial a Ats-8 le lintho tse ling tse tsoang ho dioxane ho ka kenya letsoho ho loantšeng mafu a baktheria le a fungal, haholo-holo a amanang le mefuta e hanyetsanang le lithethefatsi.Lintho tse ling tse tsoang ho dioxane li bonts'itse ts'ebetso ea cytotoxic khahlano le lisele tsa mofetše, tse ka kenyang letsoho kholisong ea li-agent tse ncha tse sebetsang tsa chemotherapeutic.Lithuto tse ling lia hlokahala ho utloisisa mokhoa oa ts'ebetso le ho hlahloba katleho ea Ats-8 ho thibela kholo ea lisele tsa mofetše. Tšimo ea mahlale a lintho tse bonahalang ke sebaka se seng se ka ruang molemo ho tsoa ho dioxane derivatives.Lik'hemik'hale tsena li na le thepa e khahlisang joalo ka solubility, botsitso, le litšoaneleho tsa optical tse etsang hore li hohele lits'ebetso tse fapaneng tsa indasteri.Li ka sebelisoa ka mokhoa o ka sebelisoang ha ho etsoa li-polymers, li-plastiki le lisebelisoa tse ling tse nang le thepa e lakatsehang. Ho bohlokoa ho hlokomela hore le ha ts'ebeliso e ka bang teng ea lihlahisoa tsa dioxane, ho kenyeletsoa Ats-8, e ts'episa, ho hlokahala lipatlisiso tse ling ho hlahloba ka botlalo. lits'ebetso.Sena se kenyelletsa ho etsa lithuto tse felletseng ho lekola mesebetsi ea bona ea tlhaho, boemo ba chefo, le litlamorao tse ka bang teng.Ho feta moo, ho ntlafatsa ts'ebetso ea ts'ebetso le ho nts'etsapele mekhoa ea scalable bakeng sa tlhahiso ea lihlahisoa tsena le tsona ke tsa bohlokoa bakeng sa lisebelisoa tsa indasteri.Qetellong, (4R-Cis) -1,1-dimethylethyl-6-cyanomethyl-2,2-dimethyl-1, 3-dioxane-4-acetate (Ats-8) ke ea sehlopha sa lihlahisoa tsa dioxane tse bonts'ang lits'ebetso tse ka bang teng mafapheng a fapaneng.Le hoja tšebeliso ea eona e nepahetseng e ka 'na ea hloka lipatlisiso tse eketsehileng, lihlahisoa tsa dioxane ka kakaretso li bontšitse tšepiso lipatlisisong tse thibelang likokoana-hloko, nts'etsopele ea lithethefatsi tse thibelang mofetše, le saense ea lintho tse bonahalang.Patlisiso e tsoelang pele le nts'etsopele ea metsoako ena e ka lebisa likhethong tse ncha tsa kalafo le lisebelisoa tse nang le thepa e ntlafalitsoeng.