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Lihlahisoa

(3aR,7aR) -4-(benzo[d]isothiazol-3-yl)octahydrospiro[is indole-2,1-piperazin]-2-ium4-methylbenzenesulfonate.CAS: 1907680-83-4

Tlhaloso e Khutšoanyane:

Nomoro ea lethathamo: XD93390
Cas: 1907680-83-4
Foromo ea molek'hule: C26H33N3O3S2
Boima ba Molek'hule: 499.68852
Boteng: E teng thepeng e teng ka lebenkeleng
Theko:  
Sephutheloana:  
Sephutheloana sa Bongata: Kopa Quote

 


Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Nomoro ea lethathamo XD93390
Lebitso la Sehlahiswa (3aR,7aR) -4-(benzo[d]isothiazol-3-yl)octahydrospiro[isoindole-2,1-piperazin]-2-ium4-methylbenzenesulfonate.
CAS 1907680-83-4
Foromo ea molek'hulela C26H33N3O3S2
Boima ba Molek'hule 499.68852
Lintlha tsa polokelo Ambient

 

Tlhaloso ea Sehlahisoa

Ponahalo Phofo e tšoeu
Assay 99% mets

 

(3aR,7aR) -4-(benzo[d]isothiazol-3-yl)octahydrospiro[isoindole-2,1-piperazin]-2-ium4-methylbenzenesulfonate, eo hape e bitsoang motsoako oa BISO, ke motsoako oa lik'hemik'hale o nang le sebopeho se ikhethileng se ikalimang ho sebelisoa tse 'maloa lefapheng la k'hemistri ea bongaka le nts'etsopele ea lithethefatsi.E 'ngoe ea ts'ebeliso e ka bang teng ea BISO ke ho phekola mafu a methapo ea kutlo.Ho ba teng ha karolo ea benzo[d]isothiazol-3-yl moeteng oa eona ho fana ka maikutlo a hore BISO e ka ba le likamano le litsamaiso tse itseng tsa methapo ea kutlo bokong, joalo ka litsamaiso tsa glutamate kapa GABAergic.Litsamaiso tsena tsa li-neurotransmitter li ameha mafung a mangata a methapo a kang lefu la sethoathoa, matšoenyeho le mathata a maikutlo.Bafuputsi ba ka batlisisa bokhoni ba BISO ba ho fetola litsamaiso tsena le ho hlahisa litlhare tse ncha tsa kalafo bakeng sa maemo a methapo. lipheo tsa tlhaho.Sebopeho sa eona sa mahlakore a mararo le boteng ba lihlopha tse sebetsang li ka sebelisana le li-receptor kapa li-enzyme tse itseng, e leng se lumellang ho etsoa ha meriana e khethiloeng le e matla.Bafuputsi ba ka sebelisa mokhoa ona oa sebopeho ho hlahisa limolek'hule tse nyenyane tse lebisang li-receptor tse amehang maloetseng a sa tšoaneng, a kang kankere, lefu la pelo le methapo ea mali, kapa mafu a tšoaetsanoang.Ho feta moo, sebopeho sa spirocyclic sa BISO le sehlopha sa ammonium se lefshoang se etsa hore e be mokhethoa ea ka khonang bakeng sa mekhoa ea ho fana ka lithethefatsi.Ho ba teng ha sehlopha se qosoang ho lumella ho thehoa ha li-ionic complexes tse nang le limolek'hule tse mpe, tse kang nucleic acid kapa liprotheine.Li-complex tsena li ka thusa ho fana ka limolek'hule tsa bioactive liseleng kapa liseleng tse itseng, ho ntlafatsa katleho ea phekolo ha ho ntse ho fokotsa litla-morao tsa tsamaiso.Sebopeho sa eona se ikhethang se fana ka menyetla ea hore litsebi tsa lik'hemik'hale tsa meriana li hlahlobe thepa ea eona ea meriana le ho ntlafatsa bokhoni ba eona ba ho sibolla lithethefatsi.Joaloka motsoako ofe kapa ofe oa lik'hemik'hale, tšebeliso ea BISO e lokela ho khomarela melaoana le tataiso ea tšireletso e thehiloeng.Bafuputsi ba lokela ho ba hlokolosi nakong ea ho qaptjoa, ho sebetsa le ho boloka ho netefatsa polokeho le ho fokotsa likotsi. ]-2-ium4-methylbenzenesulfonate, kapa BISO, e na le ts'episo ea lits'ebetso tse fapaneng tsa k'hemistri ea bongaka le nts'etsopele ea lithethefatsi.Sebopeho sa eona se ikhethileng se fana ka menyetla ea ho sibolloa ha li-agent tse ncha tsa kalafo, litsamaiso tse lebisitsoeng tsa phepelo ea lithethefatsi, le ho feto-fetoha ha litsamaiso tsa li-neurotransmitter.Leha ho le joalo, lipatlisiso tse pharaletseng lia hlokahala ho hlakisa ka botlalo bokhoni ba eona le ho ntlafatsa ts'ebeliso ea eona lefapheng la bongaka.


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    (3aR,7aR) -4-(benzo[d]isothiazol-3-yl)octahydrospiro[is indole-2,1-piperazin]-2-ium4-methylbenzenesulfonate.CAS: 1907680-83-4