Lihlahisoa

3,4,5-Trifluorophenylboronic acid ke motsoako oa lik'hemik'hale o nang le lisebelisoa likarolong tse sa tšoaneng, ho kenyelletsa le organic synthesis, chemistry ea meriana, le saense ea thepa.Motsoako ona o tsoa ho benzene, ka liathomo tse tharo tsa fluorine (-F) le sehlopha se sebetsang sa boronic acid (-B(OH)2) se khomaretsoeng sebakeng sa 3, 4, le 5 sa phenyl ring. E 'ngoe ea litšebeliso tsa mantlha tsa 3 ,4,5-Trifluorophenylboronic acid e le mohaho o nang le mekhoa e mengata ea ho haha ​​​​mokhoeng oa tlhaho oa tlhaho.Sehlopha sa boronic acid se ka ba le maikutlo a fapaneng, joalo ka Suzuki-Miyaura cross-coupling reactions, e thusang ho theha maqhama a carbon-carbon.Karabelo ena e sebelisoa haholo ha ho etsoa limolek'hule tse rarahaneng tsa manyolo, ho kenyeletsoa meriana, lik'hemik'hale tsa agrochemical le lik'hemik'hale tse ikhethang.Ka ho kenyelletsa 3,4,5-Trifluorophenylboronic acid ka karabelo, litsebi tsa lik'hemik'hale li ka hlahisa sehlopha sa trifluoromethyl sebakeng se lakatsehang, se ka susumetsang haholo lik'hemik'hale tsa lik'hemik'hale le likokoana-hloko tsa lik'hemik'hale. ho nts'etsopele ea batho ba bacha ba sebelisang lithethefatsi.Ho ba teng ha sehlopha sa trifluoromethyl ho ka ntlafatsa lipophilicity ea motsoako, botsitso ba metabolism, le kamano e tlamang ea protheine, e leng se etsang hore e be sesebelisoa sa bohlokoa sa ho fetola thepa ea lithethefatsi.Ho feta moo, li-boronic acid li bonts'itse tšebetso khahlanong le mafu a kang mofetše, lefu la tsoekere le mafu a ho ruruha.Ka ho kenyelletsa trifluorophenylboronic acid motif, bafuputsi ba ka etsa metsoako e ncha e nang le boronic acid le trifluoromethyl pharmacophores, e ka lebisang ntlafatsong ea katleho le khetho ea merero ea ho sibolla lithethefatsi. lits'ebetsong tsa mahlale a thepa.Sebopeho sa ho hula elektronike sa sehlopha sa trifluoromethyl se ka susumetsa botsitso le ts'ebetso ea motsoako.Tšobotsi ena e thusa motsoako ho nka karolo liketsong tse fapaneng tsa polymerization, e lebisang ho thehoeng ha li-polymers tse ikhethang tse nang le thepa e ntlafalitsoeng, joalo ka botsitso bo eketsehileng ba mocheso kapa mamati a ntlafalitsoeng.Ho phaella moo, bokhoni ba sehlopha sa boronic acid ba ho etsa litšebelisano tse fetohang le diols kapa boronic esters li ka sebelisoa ha ho etsoa lisebelisoa tse arabelang, tse kang li-hydrogel, lisebelisoa tsa ho utloa, le mekhoa ea ho fana ka lithethefatsi. ts'ebetso e nepahetseng le mehato ea ts'ireletso e lokela ho nkuoa.Motsoako ona o na le kutloelo-bohloko moeeng le mongobo, 'me o lokela ho bolokoa sebakeng se phodileng, se omileng.Lisebelisoa tsa ho itšireletsa, tse kang li-gloves le likhalase, li lokela ho apesoa, 'me libaka tsa mosebetsi li lokela ho ba le moea o lekaneng.Lihlopha tsa eona tse sebetsang tsa trifluoromethyl le boronic acid li etsa hore e be mohaho o nang le mekhoa e mengata ea ho haha, e leng se nolofalletsang ho kenngoa ha thepa e ikhethang ho limolek'hule tse lebisitsoeng.Tšebeliso ea eona ho k'hemistri ea meriana le saense ea thepa e totobatsa bokhoni ba eona ba ho sibolla lithethefatsi le nts'etsopele ea lisebelisoa tse tsoetseng pele.Ka ho tsoela pele ho hlahloba thepa le ts'ebetso ea 3,4,5-Trifluorophenylboronic acid, bafuputsi ba ka sibolla lits'ebetso tse ncha tse kenyang letsoho ntlafatsong ea lithuto tse ngata.