Lihlahisoa

3-Methyl-7-(2-butyn-1-yl)-8-bromoxanthine ke motsoako oa lik'hemik'hale oa lelapa la xanthine.Li-derivatives tsa Xanthine li 'nile tsa ithutoa haholo' me li tsejoa ka mefuta e sa tšoaneng ea likopo, haholo-holo lefapheng la pharmacology.Kopo e le 'ngoe ea bohlokoa ea 3-Methyl-7-(2-butyn-1-yl) -8-bromoxanthine ke tšebeliso ea eona e ka bang teng. e le sethethefatsi bakeng sa ho phekola maemo a phefumoloho a kang asthma le lefu le sa foleng la pulmonary (COPD).Li-derivatives tsa Xanthine, ho kenyeletsoa theophylline, esale li sebelisoa moriana oa phefumoloho ka lebaka la thepa ea tsona ea bronchodilatory le anti-inflammatory.Lik'hemik'hale tsena li sebetsa ka ho phomola mesifa e boreleli moeeng le ho fokotsa ho ruruha, kahoo ho ntlafatsa mosebetsi oa phefumoloho.Ho eketsoa ha athomo ea bromine sebakeng sa 8th sa lesale la xanthine ka 3-Methyl-7-(2-butyn-1-yl) -8-bromoxanthine e ka ntlafatsa litlamorao tsa eona tsa bronchodilatory ha e bapisoa le tse ling tse tsoang ho xanthine.Phetolelo ea Bromine ka metsoako e tšoanang e bontšitsoe ho eketsa matla a bona le nako ea ketso.Ka hona, motsoako ona o ka 'na oa e-ba le bokhoni ba ho ba le bronchodilator e sebetsang haholoanyane le e tšoarellang nako e telele bakeng sa maemo a phefumoloho.Ho feta moo, xanthine e boetse e batlisisitsoe bakeng sa thepa ea bona ea neuroprotective.Li bonts'itse litlamorao tsa antioxidant le anti-inflammatory, hammoho le bokhoni ba ho ntlafatsa phallo ea mali ea boko le ho ntlafatsa ts'ebetso ea kelello.Thepa ena e etsa hore e be bakhethoa ba thahasellisang bakeng sa mafu a neurodegenerative a kang Alzheimer's le Parkinson's disease. Ho phaella lits'ebetsong tsa meriana, 3-Methyl-7- (2-butyn-1-yl) -8-bromoxanthine e ka boela ea fumana tšebeliso ea lipatlisiso tsa saense.Li-derivatives tsa Xanthine hangata li sebelisoa e le lisebelisoa tsa biochemical ho ithuta li-adenosine receptors le li-enzyme tsa phosphodiesterase.Lik'hemik'hale tsena li ka sebetsa e le li-ligands kapa li-inhibitors tse khethiloeng, tse thusang lipatlisisong tsa mekhoa e itseng ea limolek'hule le litsela. optimize thepa ea eona bakeng sa ditshebediso tse itseng.Liphetoho tse fapaneng tsa lik'hemik'hale, tse kang ho fetola, ho kenyelletsa, le ho kopanya, li ka sebelisoa ho hlahisa lihlopha tse sebetsang kapa ho fetola sebopeho sa mantlha.Liphetoho tsena li ka khona ho ntlafatsa mesebetsi ea eona ea meriana kapa tsa nolofalletsa nts'etsopele ea lihlahisoa tse nang le khetho e ntlafetseng le bioavailability.Qetellong, 3-Methyl-7-(2-butyn-1-yl) -8-bromoxanthine e na le menyetla e mengata ea ho sebelisoa meriana ea phefumoloho. , neuroprotection, le lipatlisiso tsa biochemical.Litholoana tsa eona tsa bronchodilatory li etsa hore e be mokhethoa ea tšepisang bakeng sa phekolo ea maemo a ho phefumoloha, 'me thepa ea eona e ka sireletsang methapo ea kutlo e fana ka maikutlo a tšebeliso ea mafu a neurodegenerative.Liphuputso tse ling le nts'etsopele li tla hlokahala ho hlahloba ka botlalo le ho sebelisa melemo ea motsoako ona mafapheng a fapaneng a bongaka le saense.