Lihlahisoa

2-(Trifluoromethyl) benzyl bromide ke motsoako oa lik'hemik'hale o sebelisoang haholo ho organic synthesis le e le reagent mefuteng e fapaneng ea lik'hemik'hale.Sebopeho sa eona se ikhethang, se kopantseng sehlopha sa trifluoromethyl (CF3) le karolo ea benzyl bromide, se etsa hore e be karolo e fapaneng haholo ho nts'etsopele ea meriana, agrochemicals, le thepa.Tšebeliso e le 'ngoe ea bohlokoa ea 2-(Trifluoromethyl) benzyl bromide e itšetlehile ka motsoako oa meriana.Sehlopha sa trifluoromethyl se tsebahala se na le thepa e ntle ea pharmacological, ho kenyelletsa le ho eketseha ha lipophilicity le botsitso ba metabolism.Motsoako ona o ka sebelisoa e le setsi sa bohlokoa sa mohaho bakeng sa motsoako oa bakuli ba lithethefatsi kapa metsoako e sebetsang ea meriana (APIs) k'hemistri ea meriana.Ho kenyelletsoa ha sehlopha sa trifluoromethyl ho ka fetola thepa ea pharmacokinetic ea motsoako oa ho qetela, e ka ntlafatsang matla a eona, halofo ea bophelo, le katleho ea phekolo ka kakaretso. bakeng sa ho qaptjoa ha chefo e bolaeang likokoanyana le litlama tse iqapetsoeng.Ho eketsoa ha sehlopha sa trifluoromethyl ho ka ntlafatsa bioactivity, selectivity, le botsitso ba lik'hemik'hale tsa metsoako ena.Sena se li etsa hore li atlehe haholoanyane ho tobaneng le likokoanyana tse itseng kapa mofoka ha li ntse li fokotsa kotsi e ka bang teng ho likokoana-hloko tse sa lebelloang le tikolohong.Reactivity ea lik'hemik'hale e boetse e lumella nts'etsopele ea lihlahisoa kapa lihlahisoa tse ling tse ka lokollang karolo e sebetsang ha ho sebelisoa.Ho feta moo, 2-(Trifluoromethyl) benzyl bromide e na le thuso ho saense ea lintho tse bonahalang le ho theha lisebelisoa tse tsoetseng pele.E ka sebelisoa e le reagent kapa precursor bakeng sa ho kopanya li-polymers tse nang le fluorinated, liphahlo kapa lisebelisoa tse sebetsang.Lintho tse ikhethang tsa sehlopha sa trifluoromethyl, joalo ka matla a tlase a holim'a metsi le ho hanyetsa ho senyeha ha lik'hemik'hale, li ka fetisetsoa ho lisebelisoa tse hlahisoang.Sena se nolofalletsa nts'etsopele ea lisebelisoa tse nang le nako e telele ea nako e telele, hydrophobicity ea holim'a metsi, le ho hanyetsa maemo a thata, ho etsa hore li tšoanelehe bakeng sa lits'ebetso libakeng tse kang lisebelisoa tsa elektronike, sefofane le liphahlo.Ka kakaretso, 2-(Trifluoromethyl) benzyl bromide ke motsoako oa bohlokoa organic synthesis, nts'etsopele ea meriana, agrochemicals, le mahlale a lintho tse bonahalang.Sehlopha sa eona sa trifluoromethyl se fana ka thepa e lakatsehang ho metsoako e fapaneng, se e etsa sesebelisoa sa bohlokoa bakeng sa ho fetola thepa ea pharmacological ho sibolloeng ha lithethefatsi, ho rala lik'hemik'hale tse sebetsang hantle, le ho theha lisebelisoa tse tsoetseng pele.Reactivity ea komporo e lumella ho kenyelletsoa ha eona tšebetsong e fapaneng ea lik'hemik'hale, e nolofalletsang ho kopanya hantle ha limolek'hule tse fapaneng tse nang le thepa e ntlafalitsoeng.Ka kakaretso, 2-(Trifluoromethyl) benzyl bromide e bapala karolo ea bohlokoa ho ntšetseng pele liindasteri tse ngata le lipatlisiso tsa mahlale.