2-Pyrrolidinecarboxamide,1-(2-chloroacetyl)-, (2S)- CAS: 214398-99-9
Nomoro ea lethathamo | XD93426 |
Lebitso la Sehlahiswa | 2-Pyrrolidinecarboxamide,1-(2-chloroacetyl)-, (2S)- |
CAS | 214398-99-9 |
Foromo ea molek'hulela | C7H11ClN2O2 |
Boima ba Molek'hule | 190.63 |
Lintlha tsa polokelo | Ambient |
Tlhaloso ea Sehlahisoa
Ponahalo | Phofo e tšoeu |
Assay | 99% mets |
2-Pyrrolidinecarboxamide, 1-(2-chloroacetyl)-, (2S)- ke motsoako o nang le mekhoa e sa tšoaneng lefapheng la chemistry ea tlhaho le lipatlisiso tsa meriana.Motsoako ona, o tsejoang hape e le (2S) -2-Pyrrolidinecarboxamido-2-chloroacetic acid amide, o bonts'a likarolo tsa sebopeho tse etsang hore e loketse liphetoho tse itseng tsa lik'hemik'hale le lithuto tsa baeloji.In organic synthesis, (2S) -2-Pyrrolidinecarboxamido-2-chloroacetic acid amide e ka sebelisoa e le ntho ea ho qala kapa e bohareng ka har'a motsoako oa limolek'hule tse rarahaneng.Sebopeho sa eona sa chiral, se nang le lebitso (2S), se fana ka maikutlo a hore se na le tlhophiso e khethehileng ea mahlakore a mararo ea liathomo tse ka susumetsang stereochemistry le thepa ea lihlahisoa tsa eona.Thepa ena e etsa hore e be ea bohlokoa ho moralo le tlhahiso ea lithethefatsi tse ncha le metsoako ea meriana.Ka indasteri ea meriana, (2S) -2-Pyrrolidinecarboxamido-2-chloroacetic acid amide e ithutoa ka bokhoni ba eona e le inhibitor ea li-enzyme kapa liprotheine tse amehang mekhoa e itseng ea likokoana-hloko.Patlisiso e 'ngoe e tsepamisitse maikutlo ts'ebetsong ea eona e le se thibelang li-protease tse itseng, e leng li-enzyme tse nang le karolo lits'ebetsong tse fapaneng tsa 'mele.Ka ho khetha le ho thibela li-protease tsena, liphello tse nepahetseng tsa phekolo li ka finyelloa.Ho phaella moo, (2S) -2-Pyrrolidinecarboxamido-2-chloroacetic acid amide e ka sebetsa e le selelekela sa ho qaptjoa ha li-analogue tsa peptide kapa mimetics.Limolek'hule tsena li ka etsisa sebopeho le ts'ebetso ea li-peptide tse itlhahelang ka tlhaho, ka hona tsa susumetsa sepheo kapa mesebetsi e itseng ea tlhaho.Li-analogue tse joalo li ka ba le ts'ebeliso e ka bang teng ho nts'etsopele ea lithethefatsi bakeng sa kalafo ea mafu a fapaneng, ho kenyelletsa mofets'e, mathata a metabolism le maemo a methapo ea kutlo. Ho bohlokoa ho hlokomela hore (2S) -2-Pyrrolidinecarboxamido-2-chloroacetic acid amide e sebelisoa haholo lipatlisisong tsa laboratori mme ha e amoheloe bakeng sa ts'ebeliso ea bongaka.Lisebelisoa tse ka 'nang tsa e-ba teng tsa phekolo li ntse li hlahlojoa,' me ho hlokahala lipatlisiso tse ling ho fumana polokeho le katleho ea eona ho batho. lipatlisiso tsa meriana.Sebopeho sa eona sa chiral le bokhoni ba ho thibela li-enzyme kapa liprotheine tse itseng li etsa hore e be ea bohlokoa bakeng sa nts'etsopele ea lithethefatsi tse ncha le mekhoa ea phekolo.Leha tšebeliso ea eona lipatlisisong tsa laboratori e bonts'a ts'episo, lipatlisiso tse ling lia hlokahala ho utloisisa ka botlalo bokhoni ba eona lits'ebetsong tsa bongaka.