2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one Cas:1044871-04-6
Nomoro ea lethathamo | XD90961 |
Lebitso la Sehlahiswa | 2-(3,5-Dimethyl-4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)-5,7-dimethoxyquinazolin-4(3H)-one |
CAS | 1044871-04-6 |
Foromo ea limolek'hule | C24H29N3O4 |
Boima ba Molek'hule | 423.5 |
Lintlha tsa polokelo | |
Khoutu ea Lekhetho e Kopantsoeng |
Tlhaloso ea Sehlahisoa
Ponahalo | |
Tlhahlobo | |
Bntlha ea oli | 612.6±65.0 °C(E boletsoeng esale pele) |
Botenya | 1.25±0.1 g/cm3(E boletsoeng esale pele) |
Acidity coefficient | (pKa)9.54±0.20(E boletsoeng esale pele) |
RVX-297 ke BET inhibitor e matla haholo, e sebetsang ka molomo e khethang BD2.Li-IC50 tsa RVX-297 bakeng sa BRD2(BD2), BRD3(BD2), le BRD4(BD2) e ne e le 0.08, 0.05, le 0.02 μM, ka ho latellana.RVX-297 e thibela polelo ea liphatsa tsa lefutso tse fapaneng tsa lisele tsa 'mele.Katleho ea RVX-297 mefuteng ea pele ea ho ruruha ho matla le ho itšireletsa mafung.
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