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Lihlahisoa

2-(3-Formyl-4-hydroxy-phenyl) -4-methyl-thiazole-5-carboxylic acid ethyl ester CAS: 161798-01-2

Tlhaloso e Khutšoanyane:

Nomoro ea lethathamo: XD93602
Cas: 161798-01-2
Foromo ea molek'hule: C14H13NO4S
Boima ba Molek'hule: 291.32
Boteng: E teng thepeng e teng ka lebenkeleng
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Lintlha tsa Sehlahisoa

Li-tag tsa Sehlahisoa

Nomoro ea lethathamo XD93602
Lebitso la Sehlahiswa 2-(3-Formyl-4-hydroxy-phenyl) -4-methyl-thiazole-5-carboxylic acid ethyl ester
CAS 161798-01-2
Foromo ea molek'hulela C14H13NO4S
Boima ba Molek'hule 291.32
Lintlha tsa polokelo Ambient

 

Tlhaloso ea Sehlahisoa

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Assay 99% mets

 

2-(3-Formyl-4-hydroxy-phenyl) -4-methyl-thiazole-5-carboxylic acid ethyl ester ke motsoako oa lik'hemik'hale o nang le tšepiso tšimong ea meriana ka lebaka la sebopeho sa eona se ikhethang le mesebetsi e ka bang teng ea likokoana-hloko.Motsoako ona o ka sebelisoa lits'ebetsong tse fapaneng tsa lik'hemik'hale tsa meriana le lits'ebetsong tsa ho sibolla lithethefatsi. Tšebeliso e 'ngoe e ka sebelisoang ea 2-(3-Formyl-4-hydroxy-phenyl) -4-methyl-thiazole-5-carboxylic acid ethyl ester ke ntho e qalang. bakeng sa ho qapa litlhare tse ncha.Sebopeho sa eona se na le lihlopha tse sebetsang tse ka bang le liphetoho le liphetoho, tse lumellang litsebi tsa k'hemik'hale tsa meriana ho hlahisa metsoako e fapaneng le ho etsa limolek'hule tse fapaneng tse nang le thepa e matlafalitsoeng ea meriana.Ka ho fetola motsoako ona ka mokhoa o hlophisitsoeng, bafuputsi ba ka hlahisa laebrari ea li-derivatives bakeng sa lithuto tsa kamano ea sebopeho-activity (SAR), ho hlahloba phello ea liphetoho tse fapa-fapaneng ho matla a lithethefatsi, khetho le thepa ea pharmacokinetic. Ho feta moo, motsoako ona o ka 'na oa bontša mesebetsi ea tlhaho ea tlhaho ka boeona. , e ka hlahlojoang bakeng sa mekhoa ea phekolo e ka bang teng.Ho ba teng ha reng ea thiazole le sehlopha sa formyl hammoho le karolo ea phenolic ho fana ka maikutlo a hore e ka ba le thepa ea antioxidant le anti-inflammatory.Hangata thepa ena e batloa ho nts'etsopele ea lithethefatsi, kaha e ka kenya letsoho ho thibela kapa ho phekola maloetse a sa tšoaneng a amanang le khatello ea oxidative le mekhoa ea ho ruruha, e kang lefu la pelo le methapo ea pelo kapa maemo a neurodegenerative.The 2-(3-Formyl-4-hydroxy- phenyl) -4-methyl-thiazole-5-carboxylic acid ethyl ester e ka boela ea sebelisoa ho ithuta ho thibela enzyme le ho sebelisana ha enzyme-substrate.Li-enzyme li bapala karolo ea bohlokoa lits'ebetsong tse fapaneng tsa tlhaho 'me hangata li ameha mafung.Ka ho qapa li-analogue tsa motsoako ona le ho batlisisa ho sebelisana ha tsona le li-enzyme tse itseng, bafuputsi ba ka fumana leseli mabapi le ts'ebetso ea enzymatic mme ba ka khona ho khetholla lipheo tse ncha tsa lithethefatsi, haholo-holo bakeng sa maemo a amanang le ho se sebetse ha enzymatic.Ho feta moo, motsoako ona o ka sebelisoa mekhoeng e thehiloeng ho moralo oa lithethefatsi .Sebopeho sa eona se ikhethang se etsa hore e tšoanelehe bakeng sa lithuto tsa docking le mohlala oa limolek'hule, moo bafuputsi ba ka bolelang mokhoa o tlamang oa motsoako ka liprotheine tse lebisitsoeng le ho ntlafatsa likamano tsa eona ho ntlafatsa katleho.Qetellong, 2-(3-Formyl-4-hydroxy-phenyl) -4-methyl-thiazole-5-carboxylic acid ethyl ester e bonts'a ts'ebeliso e ka bang teng ho chemistry ea meriana le ho sibolloa ha lithethefatsi.E ka sebetsa e le qaleho ea bohlokoa bakeng sa ho qaptjoa ha metsoako e ncha e nang le thepa e ntlafalitsoeng ea pharmacological.Ho feta moo, ts'ebetso ea eona ea tlhaho ea tlhaho ea tlhaho le litšebelisano le li-enzyme li etsa hore e be mokhethoa ea khahlisang bakeng sa tlhahlobo e eketsehileng lits'ebetsong tsa kalafo.Lipatlisiso tse tsoelang pele le lipatlisiso li tla senola bokhoni bo feletseng ba motsoako ona ho nts'etsopele ea meriana e mecha le ho utloisisa mekhoa ea likokoana-hloko.


  • E fetileng:
  • E 'ngoe:

  • Koala

    2-(3-Formyl-4-hydroxy-phenyl) -4-methyl-thiazole-5-carboxylic acid ethyl ester CAS: 161798-01-2