2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H) -dione CAS: 446292-07 -5
Nomoro ea lethathamo | XD93407 |
Lebitso la Sehlahiswa | 2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione |
CAS | 446292-07-5 |
Foromo ea molek'hulela | C21H21N3O5 |
Boima ba Molek'hule | 395.41 |
Lintlha tsa polokelo | Ambient |
Tlhaloso ea Sehlahisoa
Ponahalo | Phofo e tšoeu |
Assay | 99% mets |
Motsoako 2-[(2R)-2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl]-1H-isoindole-1,3(2H)-dione ke ntho e rarahaneng. molek'hule ea tlhaho e nang le lits'ebetso tse ka sebelisoang lefapheng la meriana le k'hemistri ea meriana.Ho ba teng ha motsoako oa isoindole ho bontša hore motsoako ona o na le likarolo tse itseng tsa sebopeho tse amanang le baeloji 'me li fumanoe limolek'hule tsa bioactive.Li-derivatives tsa Isoindole li tlalehiloe hore li bontša mefuta e mengata ea mesebetsi ea phekolo ea meriana, ho akarelletsa le anti-inflammatory, antitumor, le antimicrobial properties.The 2-hydroxy-3-{[4-(3-oxomorpholin-4-yl)phenyl]amino}propyl. sehlopha sa motsoako ona se na le sehlopha sa hydroxyl (OH) se kopantsoeng le ketane ea carbon e meraro, e etsang mokokotlo oa karolo ena.E boetse e na le sehlopha sa phenyl se nkeloang sebaka ke karolo ea morpholinone.Morpholine e 'nile ea sebelisoa haholo k'hemistri ea meriana ka lebaka la bokhoni ba bona ba ho sebelisana le lipakane tse fapa-fapaneng tsa likokoana-hloko' me li kenyelelitsoe lithethefatsing tse ngata tse nang le mesebetsi e sa tšoaneng. na le monyetla oa ho sebetsa e le ligand kapa modulator bakeng sa liphofu tse itseng tsa molek'hule ka har'a 'mele.Lik'hemik'hale tse thehiloeng ho carbonyl li 'nile tsa sebelisoa ha ho sibolloa lithethefatsi ho sebelisana le li-enzyme, li-receptors kapa liprotheine tse amehang mekhoeng e sa tšoaneng ea mafu.Leha ho le joalo, ntle le boitsebiso bo eketsehileng mabapi le ts'ebetso ea likokoana-hloko ea motsoako ona kapa lipakane tse khethehileng, ho thata ho fana ka tlhaloso e pharaletseng ea eona. tshebediso e ka bang teng.Liphuputso tse ling le liteko li tla hlokoa ho fumana hore na e hlile e na le litšobotsi tsa eona tsa phekolo ea meriana. ]-1H-isoindole-1,3 (2H) -dione, e nang le lihlopha tsa eona tsa isoindole le lihlopha tse sebetsang, e na le mekhoa e ka sebelisoang lefapheng la meriana le lik'hemik'hale tsa meriana.Tšebeliso ea eona e khethehileng le mokhoa oa ts'ebetso li tla hloka ho hlahlojoa ho ea pele ka lipatlisiso le liteko.