(1R,2S,5S)—6,6-DiMethyl-3-aza-bicylo[3.1.0]hexane-2-carboxylic acid Methyl ester hydrochloride CAS: 565456-77-1
Nomoro ea lethathamo | XD93398 |
Lebitso la Sehlahiswa | (1R,2S,5S)—6,6-DiMethyl-3-aza-bicylo[3.1.0]hexane-2-carboxylic acid Methyl ester hydrochloride |
CAS | 565456-77-1 |
Foromo ea molek'hulela | C9H16ClNO2 |
Boima ba Molek'hule | 205.68 |
Lintlha tsa polokelo | Ambient |
Tlhaloso ea Sehlahisoa
Ponahalo | Phofo e tšoeu |
Assay | 99% mets |
(1R,2S,5S)—6,6-DiMethyl-3-aza-bicylo[3.1.0]hexane-2-carboxylic acid Methyl ester hydrochloride ke motsoako oa lik'hemik'hale o nang le lisebelisoa tse sa tšoaneng lipatlisisong tsa meriana le nts'etsopele ea lithethefatsi.E 'ngoe ea litšebeliso tse ka sehloohong tsa motsoako ona ke mokhoa oa ho haha chiral ha ho etsoa li-intermediates tsa meriana le metsoako e sebetsang ea meriana (APIs).Sebopeho sa eona se ikhethang sa libaesekele le bokhabane li etsa hore e be ea bohlokoa tlhahisong ea metsoako e hloekileng ea enantiomerically.Ka ho kenyelletsa motsoako ona ka har'a motsoako, litsebi tsa lik'hemik'hale li ka laola stereochemistry le ho etsa thepa e khethehileng ea meriana ho limolek'hule tse hlahisoang.Sena ke sa bohlokoa ka ho khetheha ntlafatsong ea lithethefatsi, moo mosebetsi o lakatsehang oa likokoana-hloko hangata o itšetlehileng ka tlhophiso ea sebaka sa molek'hule.Ho phaella moo, (1R,2S,5S)—6,6-DiMethyl-3-aza-bicylo[3.1.0]hexane -2-carboxylic acid Methyl ester hydrochloride e sebelisoa e le selelekela sa motsoako oa lithethefatsi tse thehiloeng ho quinuclidine.Li-derivatives tsa quinuclidine li bonts'itse mefuta e mengata ea ts'ebetso ea likokoana-hloko, ho kenyeletsoa antipsychotic, anticonvulsant, le thepa ea ho kokobetsa bohloko.Ka ho hlahisa lihlopha tse itseng tse sebetsang ho motsoako, litsebi tsa lik'hemik'hale li ka fetola thepa ea eona ea pharmacokinetic le pharmacodynamic, ho matlafatsa matla a eona a phekolo.Ka lebaka la ho ba teng ha amine ea thuto e phahameng le sebopeho se sitisang sa lihlopha tsa methyl, e ka nka karolo liketsong tse fapaneng tsa lik'hemik'hale, joalo ka karabelo ea amidation, alkylation, le cycloaddition.Reactivity ea eona le bokhoni ba ho theha li-intermediates tse rarahaneng li etsa hore e be sesebelisoa se nang le mekhoa e mengata ea ho kopanya lintho tse phelang, e leng se lumellang hore ho thehoe metsoako e sa tšoaneng ea sebopeho. .0]hexane-2-carboxylic acid Methyl ester hydrochloride ke motsoako oa bohlokoa ho nts'etsopele ea lithethefatsi le organic synthesis.Sebopeho sa eona sa chirality le se ikhethang se nolofalletsa tlhahiso ea metsoako e hloekileng ea enantiomerically le motsoako oa lithethefatsi tse thehiloeng ho quinuclidine tse nang le thepa e khethehileng ea pharmacological.Reactivity ea eona e boetse e etsa hore e be reactant e sebetsang le e thusang liphetohong tse fapaneng tsa lik'hemik'hale.Ka kakaretso, motsoako ona o phetha karolo ea bohlokoa ho nts'etsopele ea lipatlisiso tsa meriana le nts'etsopele ea li-agent tse ncha tsa phekolo.