1,1-Cyclobutanedicarboxylatodiammineplatinum (II) Cas:41575-94-4
| Nomoro ea lethathamo | XD90684 |
| Lebitso la Sehlahiswa | 1,1-Cyclobutanedicarboxylatodiammineplatinum (II) |
| CAS | 41575-94-4 |
| Foromo ea limolek'hule | C6H12N2O4Pt |
| Boima ba Molek'hule | 371.25 |
| Lintlha tsa polokelo | 2-8°C |
| Khoutu ea Lekhetho e Kopantsoeng | 28439090 |
Tlhaloso ea Sehlahisoa
| Ponahalo | Phofo e tšoeu ho isa ho e tšoeu |
| Tlhahlobo | 99% |
| Metsi | ≤0.5% |
| Tahlehelo ka ho Omisa | ≤0.5% |
| Li-chloride | ≤100ppm |
| Lintho Tse Amanang | ≤0.25% |
| Tšilafalo efe kapa efe e sa Boleloeng | ≤ 0.1% |
| Litšila tse ling kaofela | ≤0.5% |
| 1,1-Cyclobutanedicarboxylic acid | ≤ 0.5% |
Lithethefatsi tsa antineoplastic tsa moloko oa bobeli oa platinum.Ts'ebetso ea antitumor le antitumor e tšoana le ea cisplatin, empa ho qhibiliha ha metsi ho molemo ho feta cisplatin, 'me chefo ea liphio le eona e tlase.E na le phello e ntle ea ho phekola kankere e nyenyane ea lisele tsa matšoafo, kankere ea mahe a bomme, hlooho le molala squamous cell carcinoma, hlahala ea testicular, malignant lymphoma, joalo-joalo. E ka boela ea sebelisoa bakeng sa mofetše oa popelo, kankere ea senya, joalo-joalo.
Lithethefatsi tse thibelang mofetše oa platinum tsa moloko oa bobeli li na le mesebetsi le ts'ebeliso e tšoanang le ea cisplatin.E sebetsa ho feta cisplatin bakeng sa lihlahala tse ling, 'me e matla ho feta cisplatin e le radiosensitizer tlas'a maemo a hypoxic.Haholo-holo e sebelisoa bakeng sa mofetše oa mahe a bomme, mofetše oa testicular, mofetše o monyane oa lisele tsa matšoafo le mofetše oa hlooho le molala.
Carboplatin ke sethethefatsi sa anticancer se thehiloeng platinum se senyang DNA ka ho theha khokahano ea intrachain ho masalla a haufi a guanine.Phello ea antitumor ea lithethefatsi tsena e finyelloa ka ho lahleheloa ke ts'ebetso ea ho lokisoa ha DNA e sa lumellaneng (ente ea MMR) le ho kenngoa ha lefu la lisele tse hlophisitsoeng.
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