Lihlahisoa

1-Methyl-4-pyrazole boronic acid pinacol ester ke motsoako o nang le mefuta e mengata ea likopo, haholo-holo tšimong ea organic synthesis.Sebopeho sa eona se ikhethang le ts'ebetso ea ts'ebetso e etsa hore e be ea bohlokoa liketsong tse fapa-fapaneng tsa lik'hemik'hale 'me e le mohaho oa mohaho oa motsoako oa limolek'hule tse rarahaneng.E 'ngoe ea lisebelisoa tsa bohlokoa tsa 1-Methyl-4-pyrazole boronic acid pinacol ester ke ho thehoa ha carbon-carbon kapa litlamo tsa carbon-heteroatom.Sehlopha sa boronic acid ka har'a molek'hule se ka etsa liphetoho tse amanang le Suzuki-Miyaura, se nolofalletsang ho hokela karolo ea 1-methyl-4-pyrazole ho metsoako e meng kapa lihlopha tse sebetsang.Boitšoaro bona bo lumella litsebi tsa lik'hemik'hale hore li thehe metsoako e rarahaneng ea lintho tse phelang tse nang le mekhoa e metle le thepa.Ho phaella moo, sehlopha sa pinacol ester ka molek'hule se fana ka botsitso le ho sireletsa mosebetsi oa boronic acid nakong ea liketso tse sa tšoaneng.Sehlopha sena se sireletsang se ka tlosoa habonolo tlas'a maemo a bonolo, kahoo se pepesa sehlopha sa boronic acid bakeng sa liphetoho tse ling.Ka lebaka leo, 1-Methyl-4-pyrazole boronic acid pinacol ester e sebetsa e le setsi se nang le mekhoa e mengata ea ho kopanya meriana, agrochemicals le lik'hemik'hale tse ling tse ntle. bakhethoa ba lithethefatsi.Ka ho sebelisa 1-Methyl-4-pyrazole boronic acid pinacol ester e le ntho ea ho qala, litsebi tsa lik'hemik'hale li ka hlahisa karolo ea 1-methyl-4-pyrazole ka molek'hule e reretsoeng, e fana ka likarolo tse itseng kapa mesebetsi.Lik'hemik'hale tse hlahisoang li ka 'na tsa bontša ts'ebetso e ntlafetseng ea likokoana-hloko, pharmacokinetics e ntlafetseng, kapa chefo e fokotsehileng.Ho feta moo, 1-Methyl-4-pyrazole boronic acid pinacol ester e bohlokoa ho saense ea lintho tse bonahalang le catalysis.E ka sebetsa e le ligand, e hokahanyang le li-catalysts tsa tšepe le ho kenya letsoho liketsong tse fapaneng tsa catalytic.Sehlopha sena sa boronic acid se ka etsa li-complexes tse nang le litšepe tsa phetoho, tse lumellang ts'ebetso ea CH bond kapa catalysis ea cross-coupling reactions.Ka kakaretso, 1-Methyl-4-pyrazole boronic acid pinacol ester ke motsoako o nang le mekhoa e mengata e nang le ts'ebeliso ea bohlokoa ho organic synthesis, pharmaceuticals, material science, le catalysis.Ts'ebetso ea eona ea boronic acid le pinacol ester sehlopha li etsa hore e be molemo bakeng sa karabelo ea bond ea carbon-carbon kapa carbon-heteroatom, e nolofalletsang kaho ea limolek'hule tse rarahaneng.Ts'ebeliso ea eona e ama liindasteri tse fapaneng, ho kenyeletsoa tlhophiso ea meriana, nts'etsopele ea lisebelisoa tse sebetsang, le nts'etsopele ea litsamaiso tsa catalytic.Ho feto-fetoha ha maemo le ho sebetsa hape ha 1-Methyl-4-pyrazole boronic acid pinacol ester ho etsa hore e be sesebelisoa sa bohlokoa bakeng sa litsebi tsa k'hemistri tse sebetsanang le ho qaptjoa ha metsoako ea lipale le moralo oa litharollo tse ncha.