Lihlahisoa

1-Methyl-4-pyrazole boronic acid pinacol ester ke motsoako oa lik'hemik'hale o bapalang karolo ea bohlokoa lefapheng la chemistry ea tlhaho le ho sibolloa ha lithethefatsi.E na le karolo ea boronic acid, e etsang hore e be mohaho oa bohlokoa oa ho haha ​​​​mohaho oa limolek'hule tse sa tšoaneng.E 'ngoe ea lisebelisoa tse ka sehloohong tsa 1-Methyl-4-pyrazole boronic acid pinacol ester e le tšimong ea lik'hemik'hale tsa meriana.Hangata e sebelisoa e le selelekela kapa se mahareng ha ho etsoa metsoako ea meriana.Li-acid tsa boronic li tsejoa ka bokhoni ba tsona ba ho etsa li-complexes tse tsitsitseng ka li-enzyme tse itseng, haholo-holo li-protease.Thepa ena e ba etsa lisebelisoa tse loketseng tsa ho etsa li-enzyme inhibitors tse ka lebisang mafu a itseng.Ka ho kenyelletsa karolo ea pyrazole ka har'a asiti ea boronic, motsoako o hlahisoang o bonts'a kamano e matlafalitsoeng ea tlamahano le khetho ho enzyme e shebiloeng.Sena se etsa 1-Methyl-4-pyrazole boronic acid pinacol ester moaho oa bohlokoa bakeng sa boiteko ba ho sibolla lithethefatsi bo lebisitseng mafu a thehiloeng ho protease joalo ka mofetše, ho ruruha, le mafu a vaerase. pinacol ester e ka ba le liphetoho tse fapaneng tsa lik'hemik'hale, joalo ka karabelo ea li-cross-coupling ea Suzuki-Miyaura le karabelo ea Heck.Liphetoho tsena li lumella ho thehoa ha carbon-carbon bonds, ho nolofatsa mokhoa oa ho kopanya metsoako e rarahaneng ea lintho tse phelang.Sehlopha sa pyrazole se eketsa mefuta-futa le ts'ebetso ho metsoako e entsoeng, ho etsa hore 1-Methyl-4-pyrazole boronic acid pinacol ester e be reagent e fapaneng ho organic synthesis. Ho feta moo, 1-Methyl-4-pyrazole boronic acid pinacol ester e bontšitse bokhoni nts'etsopele ea lisebelisoa tse thehiloeng ho boron.Sehlopha sa boronic acid se na le thepa e ikhethang e etsang hore e khone ho kenya letsoho mekhoeng ea ho iketsetsa, e lebisang ho thehoeng ha mehaho ea supramolecular.Bokhoni bona bo 'nile ba hlahlojoa tšimong ea mahlale a thepa ho etsa lisebelisoa tse sebetsang, tse kang li-gel, lifilimi, le li-nanoparticles, tse ka fumanang likopo ho lisebelisoa tsa elektronike, catalysis le ho fana ka lithethefatsi.Ka kakaretso, 1-Methyl-4-pyrazole boronic acid. pinacol ester ke motsoako o nang le mefuta e mengata e fapaneng ea likopo.Ts'ebetso ea eona ea boronic acid e lumella ho kopanngoa ha limolek'hule tse rarahaneng, e leng se etsang hore e be mohaho oa bohlokoa oa ho sibolloa ha lithethefatsi le motsoako oa manyolo.Ntle le moo, thepa ea eona e ikhethang e etsa hore ho thehoe lisebelisoa tsa supramolecular tse nang le ts'ebeliso ea likarolo tse fapaneng.Ka kakaretso, tlhaho ea eona e nang le mefuta e mengata e etsa hore 1-Methyl-4-pyrazole boronic pinacol ester e be sesebelisoa sa bohlokoa bakeng sa bafuputsi ba lithuto tse fapaneng tsa saense.