Lihlahisoa

(αS,3S) -α-[(tert-Butyloxycarbonyl) amino] -2-oxo-3-pyrrolidinepropanoic acid methyl ester, eo hape e tsejoang e le Boc-Amino acid methyl ester, ke motsoako oa bohlokoa tšimong ea organic synthesis le peptide. chemistry.Boc-Amino acid methyl ester e sebetsa e le mokhoa o sirelelitsoeng oa amino acid, moo sehlopha sa Boc (tert-butyloxycarbonyl) se sebelisetsoang ho sireletsa sehlopha sa amino nakong ea liketso.Motsoako ona o sebelisoa haholo-holo ka peptide synthesis ho hlahisa li-amino acid tse khethehileng ka liketane tsa peptide.Ba kenya letsoho lits'ebetsong tse fapaneng tse kang pontšo, taolo ea enzyme, le tšehetso ea sebopeho.Peptide synthesis e kenyelletsa ho kopana ha li-amino acid ka mohato ho etsa tatelano e itseng e etsisang li-peptide tsa tlhaho kapa ho theha meaho e ncha e nang le thepa e lakatsehang. e 'ngoe ea mekhoa e sebelisoang haholo ho etsa li-peptide.Ho SPPS, ketane ea peptide e entsoe ka mokhoa oa mohato ho tšehetso e tiileng, hangata e sebelisa motsoako oa amino acid o nang le sehlopha se sireletsang nakoana.Boc-Amino acid methyl ester ke sesebelisoa se loketseng sa ho qala bakeng sa SPPS ka lebaka la botsitso, ho qhibiliha le ho lumellana le li-reagents tse ling tsa peptide synthesis.During peptide synthesis, Boc-Amino acid methyl ester e kenyelletsoa ketane ea peptide e ntseng e hōla ka ho thehoa ha amide bond.Sehlopha se sirelletsang sa Boc se thibela maikutlo a sa batleheng mme se etsa bonnete ba ho kopanya ho khethehileng ha amino acid le ketane ea peptide.Hang ha tatellano e lakatsehang e finyelloa, sehlopha sa Boc se tlosoa tlas'a maemo a bonolo, se senola sehlopha sa mahala sa amino bakeng sa liphetoho tse ling kapa sebopeho sa peptide. Ho phaella ho peptide synthesis, Boc-Amino acid methyl ester e ka boela ea sebelisoa ha ho etsoa litlhare tse fapa-fapaneng. li-intermediates, agrochemicals, le metsoako e meng ea manyolo.Ho sebetsana le eona habonolo, botsitso, le ho lumellana le maemo a tloaelehileng a ho itšoara ho etsa hore e be mohaho o nang le mekhoa e mengata ea ho haha ​​​​bakeng sa organic synthesis.Ka kakaretso, Boc-Amino acid methyl ester ke sesebelisoa sa bohlokoa ho peptide synthesis le organic chemistry.Karolo ea eona e le mofuta o sirelelitsoeng oa li-amino acid e lumella ho bokelloa ka nepo ha liketane tsa peptide le ho theha meaho e fapaneng ea li-peptide bakeng sa lipatlisiso, ho sibolloa ha lithethefatsi le lits'ebetso tsa kalafo.